AMAT Nurmuhammat;EKIM Mahsum;EIZIZ Ranagul;SIDIK Axirjan;TRIM Halidam;TOHTI Patigul;OBUL Buhliqam;TURDI Nabijan;UPUR Halmurat
In this paper the epidemiology of vitiligo and immune function in view of syndrome characteristics of traditional Uighur medicine are studied. Epidemiological investigation for syndrome characteristics of the traditional Uygur medicine in vitiligo patients who stayed in the department of Dermatology of the Kashgar Uighur Medical Hospital was introduced, including general information and clinical symptoms. The factors including CD3+, CD4+, CD8+, CD25+, IL-2, IL-4, IL-6, IL-8, ICAM-1, IFN-γ, TNF-а, were respectively detected by flow cytometry technique and enzyme-linked immunosorbent assay (ELISA) in whole blood. The results show that the female patients (57.92%) outnumber the male patients (42.08%). The amount of patients aging among 3-15 (36.61%) is more than that of the other aging groups. The proportions of four abnormal Hilit groups are descripted as the following order: Abnormal Balgham group> Abnormal Savda group>Abnormal Sapra group>Abnormal Khan group. In comparison with the normal group (P<0.05), the plasma level of vitiligo patients on CD8+, IL-2, IL-6, IL-8, IFN-γ, TNF-а, ICAM-1 increased and the level on CD3+, CD25+, IL-4 decreased in abnormal and normal balhgam syndrome. There were not obviously differences among level of CD3+CD25+IL-4, IL-6, IL-8, in abnormal and normal Balgham syndrome(P<0.05). It is concluded that the abnormal Balgham is the main syndrome in the traditional Uighur medicine. The level of CD3+, CD25+, IL-4, IL-6, IL-8 are closely related with Uighur Medicine Abnormal Balgham, especially the change of some immunity parameter may be indicated to the abnormal Abnormal Balgham of vitiligo.